\n\tmtctheme_content = “Are you suffering from knee and hip pain and stiffness? You may have osteoarthritis, a disease that affects millions of people worldwide. Fortunately, a potentially existing medical protocol of Gold Particle Injections may offer an alternative to expensive procedures like knee replacement therapy.rnrn
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rnRheumatoid arthritis and osteoarthritis are two common forms of arthritis. Although they can cause similar symptoms, there are some differences between the two.rnrnRheumatoid arthritis is an inflammatory disease in which your immune system attacks your joints, especially the hands, wrists, and feet. People with rheumatoid arthritis can have joint stiffness that lasts for hours.\n Havard Health<\/p>\n Is it osteoarthritis or rheumatoid arthritis?<\/strong><\/p>\n 'Occasionally, prolonged joint stiffness in the morning is the first symptom of rheumatoid arthritis.'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[1]<\/sup><\/span>rnrnOsteoarthritis is a chronic disease that also causes joints to become painful and stiff. The joints that are most often affected are the knee and hips. Problems in the small joints of the hands are also common.\n Public Health England<\/p>\n Symptoms of osteoarthritis<\/strong><\/p>\n 'Almost any joint can be affected by osteoarthritis, but the condition most often causes problems in the knees, hips and small joints of the hands.'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[2]<\/sup><\/span>rnrnOsteoarthritis can have a significant impact on your quality of life and productivity. Chronic pain makes it challenging to complete even the simplest daily activities. That is why osteoarthritis is the leading cause of disability worldwide.\n Medscape<\/p>\n Osteoarthritis<\/strong><\/p>\n 'On the basis of the radiographic criteria for osteoarthritis, more 50% of adults older than 65 years are affected by the disease. Internationally, osteoarthritis is the most common articular disease.'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[3]<\/sup><\/span>rnrnAs discussed previously, there is no cure for these diseases. Many patients rely on painkillers, which have limited efficacy. Thus, the use of injections is a promising alternative to reduce inflammation and pain in your joints.rnrn<\/p>\n<\/div>rnrn\n Cochrane Library<\/p>\n Injectable gold for rheumatoid arthritis<\/strong><\/p>\n '...in the past decade the use of injectable gold for rheumatoid arthritis has markedly declined, and its clinical usefulness has been doubted.'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[4]<\/sup><\/span>rnrnIn turn, Gold Particles Injection may help to reduce joint pain and inflammation in both conditions. As Dr. Robert MacLauchlan explains in this video, 20 milligrams of small gold particles are used to suppress the pain and the inflammation of joints only when needed.rnrnThese particles interact with the bodyu2019s immune system, stimulating the release of substances to stop pain and inflammation pathways. The level of inflammation determines how much of the ion complexes are released from the microparticles.rnrn rnrnOne of the greatest things about this treatment is that it allows people to have the freedom and mobility without the pain that they were experiencing before. We’ve had people be able to go up and downstairs, not just like one floor, but go up and downstairs at a lighthouse.rnrn<\/p> - Dr. Robert MacLauchlan<\/strong><\/p><\/div>rnrn UW Medicine<\/p>\n About gold treatment<\/strong><\/p>\n 'In general oral gold may cause fewer side effects but may not be as effective as injectable gold.'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[5]<\/sup><\/span>rnrnAlthough gold shots have become rare, some scientists still believe gold salts deserve a second chance.rnrn rnrnWe shouldn’t dismiss gold salts so quickly. We scientists have really never understood why gold works. Now that we have a better handle on its action, we may be able to use that mechanism to create new and better gold-like drugs to treat arthritis.\n Science Daily<\/p>\n How Gold Salts Ease Pain Of Arthritis<\/strong><\/p>\n 'Dr. David Pisetsky, chief of the division of rheumatology and immunology in the department of medicine at Duke, says we shouldn't dismiss gold salts so quickly. We scientists have really never understood why gold works....'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[6]<\/sup><\/span>rnrn<\/p> - Dr. David Pisetsky<\/strong><\/p><\/div>rnrnDr. David Pisetsky is the chief of the division of rheumatology and immunology in the Duke University Department of Medicine.rnrn\n Drug Bank<\/p>\n Sodium aurothiomalate<\/strong><\/p>\n 'It is known that sodium aurothiomalate inhibits the synthesis of prostaglandins'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[7]<\/sup><\/span> Aurothioglucose inhibits the activity of an enzyme called adenylyl cyclase in our immune cells, blocking the action of pro-inflammatory substances.\n Drug Bank<\/p>\n Aurothioglucose<\/strong><\/p>\n 'In particular, such inhibition of the activity of adenylyl cyclase and its various isoforms would theoretically also limit the cyclases' ability to induce mast cell degranulation and histamine release...all of which are pro-inflammatory actions'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[8]<\/sup><\/span>rnrnAuranofin can also suppress inflammation by inhibiting the activity of certain enzymes.\n Drug Bank<\/p>\n Auranofin<\/strong><\/p>\n 'Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and stimulate cell-mediated immunity.'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[9]<\/sup><\/span>rnrn\n Aalborg University Hospital<\/p>\n Pilot Study > Results<\/strong><\/p>\n 'Pain and function improved in 25 of 30 patients. Womac pain decreased from 9 (6-16) to 3 (0-15), stiffness from 4 (1-8) to 2 (0-8), function from 29 (14-51) to 11 (0- 41) (Figure 4), PainDetect decreased from 10 (1-26) to 3 (0-19) (Figure 5)...'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[10]<\/sup><\/span>rn<\/p>\n rn t<\/p>\n rn t<\/p>\n rn t<\/p>\n rn<\/ul>\n rnThe authors of the study concluded that intra-articular metallic gold improved joint pain, stiffness, and function. The therapy relieved pain and enhanced function in more than 80% of the patients.\n Aalborg University Hospital<\/p>\n Pilot Study > Results<\/strong><\/p>\n 'Pain and function improved in 25 of 30 patients.'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[11]<\/sup><\/span>rnrnA study investigated the effects of metallic gold implanted around painful joints in animal models. Dogs with pain and loss of function due to hip dysplasia that received gold transplants had less pain and loss of function compared to those that didnu2019t.rnrnAfter two years, 80% of the animals still showed a positive effect of the treatment, with reduced pain and better quality of life.\n Science Daily<\/p>\n Pain Of Dysplasia In Dogs<\/strong><\/p>\n 'After two years, 80% of the dogs still showed a positive effect of treatment.'<\/em><\/p>\n View in Article<\/a>\n <\/div>\n \">[12]<\/sup><\/span>rnrn\n Gold Injections for Rheumatoid Arthritis vs. Osteoarthritis<\/h2>\n rnrnDoctors have been using gold injections to treat rheumatoid arthritis since the early 20th century. Injections made of gold salts, including auranofin and gold sodium thiomalate, were used to reduce joint pain and inflammation.rnrnHowever, their use started to decline in the ’90s due to the occurrence of side effects, giving place to other injections such as methotrexate, hyaluronic acid, platelet-rich plasma, and placental tissue matrix.\n
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Do They Still Give Gold Shots for Arthritis?<\/h2>\n rnrnMyocrisin (Sodium aurothiomalate) and Solganal (aurothioglucose) injections are no longer available in the U.S. The FDA-approved gold salt Auranofin is an oral capsule indicated for rheumatoid arthritis treatment.rnrnHowever, oral gold may not be as effective as injected gold. Also, it offers more toxicity than other drugs used in the treatment of arthritis.\n
Is Gold Anti-Inflammatory?<\/h2>\n rnrnGold salts are known for their immunosuppressive and anti-inflammatory effects. The mechanism of action of these drugs is not fully understood.rnrnSodium aurothiomalate may inhibit the synthesis of prostaglandins (hormones created at the injury site).\n
What Are the Benefits of Gold Therapy?<\/h2>\n rnrnA pilot study conducted at the Aalborg University Hospital, Aalborg, Denmark investigated the role of gold ions in treating knee osteoarthritis. Thirty patients with moderate to severe knee osteoarthritis received a single injection of metallic gold (20 mg) into the knee joint. The researchers observed the following benefits of the therapy:\n
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Gold Injections From Sodium Aurothiomalate vs. Gold Particles for Knee\/Hip Pain<\/h2>\n rn<\/p>\n