Statistics on Sickle Cell Anemia<\/h2>\n rnrnAccording to the Center of Disease Control (CDC)<\/a> in the USA, the statistics relating to Sickle Cell Anemia:rn<\/p>\nrn t<\/p>\n- Approximately 100,000 Americans are affected by SCD.<\/li>\n
rn t<\/p>\n
- 1 out of every 16,300 Hispanic-American<\/strong> children is born with SCD.<\/li>\n
rn t<\/p>\n
- About 1 out of every 365 Black or African-American<\/strong> births suffer from SCD.<\/li>\n
rn t<\/p>\n
- About 1 in 13 Black or African-American babies are born with sickle cell trait (SCT).<\/li>\n
rn<\/ul>\n
rnEven from the Public Health<\/strong> point of view, SCD is a major concern. Approximately 75,000 hospitalizations<\/strong> were documented in the USA from 1989 to 1993, due to SCD, costing approximately $475 million.<\/strong>rnrn\n What is Sickle Cell Anemia?<\/h2>\n rnrnSickle Cell Anemia is a Genetic disorder.<\/strong> The basic defect lies in the structure of Hemoglobin. Hemoglobin is the oxygen-carrying component<\/strong> of the blood.rnrnDue to this defect, the Red Blood Cells (RBCs) which are normally disc-shaped, become sickle-shaped<\/strong>. This is sometimes known as Sickling of RBCs.rnrnThis sickling also makes them rigid. The final result is decreased oxygen-carrying capacity<\/strong> of the blood, leading to a decline in the health of various organs and tissues.rnrn![\"\"](\"https:\/\/mtctheme.medicaltourismco.com\/wp-content\/uploads\/archive\/2019\/04\/Anemia.jpg\")
rn<\/p>\nSickle Cell Anemia<\/h5>\n
rnSickle Cell Anemia can be of two main kinds:rn<\/p>\n
rn t<\/p>\n- Sickle Cell Disease:<\/strong> This happens when the child inherits one defective gene from each parent, making it a defective pair. This is the severe form of sickle cell anemia.<\/li>\n
rn t<\/p>\n
- Sickle Cell Trait:<\/strong> Individuals who inherit one defective and one healthy gene<\/strong> are said to be carriers of the sickle cell trait. The symptoms, in this case, may be mild or non-existent.<\/li>\n
rn<\/ul>\n
rn\n
What Are the Symptoms?<\/h2>\n rn<\/p>\n
\nSymptoms of Sickle Cell Anemia<\/strong><\/caption>\nrn<\/p>\n
rn<\/p>\nrn<\/p>\nSymptom<\/th>\nrn<\/p>\n
Explanation<\/th>\nrn<\/tr>\n
rn<\/p>\n
rn<\/p>\nAnemia<\/strong><\/td>\nrn<\/p>\n
The deficiency of oxygen<\/strong> in the circulation will cause anemia. The patient will have a pale appearance.<\/strong><\/td>\nrn<\/tr>\n
rn<\/p>\n
rn<\/p>\nPain episodes<\/strong><\/td>\nrn<\/p>\n
Pain in SCAD can either be vaso-occlusive pain or neuropathic pain.rnrnVaso-occlusive pain<\/strong> is caused when the inflexible sickle-shaped RBCs block the blood supply to the bones and joints.rnrnNeuropathic pain<\/strong> occurs when the blood doesnu2019t reach the nerves in the body.rnrnThe patientu2019s hands and feet might also show swelling<\/strong> due to these blockages in the blood vessels.rnrnThese pain episodes are also known as Crises.<\/td>\nrn<\/tr>\n
rn<\/p>\n
rn<\/p>\nFrequent Infection<\/strong>s<\/td>\nrn<\/p>\n
The spleen<\/strong> is the organ which helps fight infections.<\/strong> If it doesnu2019t receive the required amount of oxygen and nutrients, it will be ineffective.<\/td>\nrn<\/tr>\n
rn<\/p>\n
rn<\/p>\nDelayed growth<\/strong><\/td>\nrn<\/p>\n
The body, on the whole, needs its regular supply of nutrients and oxygen<\/strong>. In the absence of these, the growth of various organs and tissues is stunted.<\/td>\nrn<\/tr>\n
rn<\/p>\n
rn<\/p>\nVision problems<\/strong><\/td>\nrn<\/p>\n
Blood vessels supplying the tissues of the eyes are very narrow. Their blockage will lead to a damaged Retina<\/strong>. This may cause blurring or loss of vision.<\/strong><\/td>\nrn<\/tr>\n
rn<\/tbody>\n
rn<\/table>\n
rn\n
Why Stem Cell Therapy for Sickle Cell Anemia?<\/h2>\n rnrnStem cell treatment works on the principle of Regeneration<\/strong>. The mother cells (stem cells)<\/strong> extracted from the donor are activated and infused into the recipientu2019s body.rnrnStem cells divide into daughter cells<\/strong>. These daughter cells are guided into becoming specific cells<\/strong> which promote repair response of injured or diseased tissue. These are known as Induced Pluripotent Stem Cells (IPSCs). <\/strong>rnrnThus, stem cells can be used to treat a large number of degenerative diseases.<\/strong> Here are some of these diseases:rn<\/p>\n
rn t<\/p>\n
rn t<\/p>\n
rn t<\/p>\n
rn<\/ul>\n
rnEven from the Public Health<\/strong> point of view, SCD is a major concern. Approximately 75,000 hospitalizations<\/strong> were documented in the USA from 1989 to 1993, due to SCD, costing approximately $475 million.<\/strong>rnrn\n rnSickle Cell Anemia can be of two main kinds:rn<\/p>\n rn t<\/p>\n rn<\/ul>\n rn\n rn<\/p>\n rn<\/p>\n rn<\/tr>\n rn<\/p>\n rn<\/p>\n rn<\/tr>\n rn<\/p>\n rn<\/p>\n rn<\/tr>\n rn<\/p>\n rn<\/p>\n rn<\/tr>\n rn<\/p>\n rn<\/p>\n rn<\/tr>\n rn<\/p>\n rn<\/p>\n rn<\/tr>\n rn<\/tbody>\n rn<\/table>\n rn\n What is Sickle Cell Anemia?<\/h2>\n rnrnSickle Cell Anemia is a Genetic disorder.<\/strong> The basic defect lies in the structure of Hemoglobin. Hemoglobin is the oxygen-carrying component<\/strong> of the blood.rnrnDue to this defect, the Red Blood Cells (RBCs) which are normally disc-shaped, become sickle-shaped<\/strong>. This is sometimes known as Sickling of RBCs.rnrnThis sickling also makes them rigid. The final result is decreased oxygen-carrying capacity<\/strong> of the blood, leading to a decline in the health of various organs and tissues.rnrn
rn<\/p>\nSickle Cell Anemia<\/h5>\n
rn t<\/p>\n
What Are the Symptoms?<\/h2>\n rn<\/p>\n
\n
rn<\/p>\n Symptom<\/th>\n Explanation<\/th>\n rn<\/p>\n Anemia<\/strong><\/td>\n The deficiency of oxygen<\/strong> in the circulation will cause anemia. The patient will have a pale appearance.<\/strong><\/td>\n rn<\/p>\n Pain episodes<\/strong><\/td>\n Pain in SCAD can either be vaso-occlusive pain or neuropathic pain.rnrnVaso-occlusive pain<\/strong> is caused when the inflexible sickle-shaped RBCs block the blood supply to the bones and joints.rnrnNeuropathic pain<\/strong> occurs when the blood doesnu2019t reach the nerves in the body.rnrnThe patientu2019s hands and feet might also show swelling<\/strong> due to these blockages in the blood vessels.rnrnThese pain episodes are also known as Crises.<\/td>\n rn<\/p>\n Frequent Infection<\/strong>s<\/td>\n The spleen<\/strong> is the organ which helps fight infections.<\/strong> If it doesnu2019t receive the required amount of oxygen and nutrients, it will be ineffective.<\/td>\n rn<\/p>\n Delayed growth<\/strong><\/td>\n The body, on the whole, needs its regular supply of nutrients and oxygen<\/strong>. In the absence of these, the growth of various organs and tissues is stunted.<\/td>\n rn<\/p>\n Vision problems<\/strong><\/td>\n Blood vessels supplying the tissues of the eyes are very narrow. Their blockage will lead to a damaged Retina<\/strong>. This may cause blurring or loss of vision.<\/strong><\/td>\n Why Stem Cell Therapy for Sickle Cell Anemia?<\/h2>\n rnrnStem cell treatment works on the principle of Regeneration<\/strong>. The mother cells (stem cells)<\/strong> extracted from the donor are activated and infused into the recipientu2019s body.rnrnStem cells divide into daughter cells<\/strong>. These daughter cells are guided into becoming specific cells<\/strong> which promote repair response of injured or diseased tissue. These are known as Induced Pluripotent Stem Cells (IPSCs). <\/strong>rnrnThus, stem cells can be used to treat a large number of degenerative diseases.<\/strong> Here are some of these diseases:rn<\/p>\n
![\"\"](\"https:\/\/mtctheme.medicaltourismco.com\/wp-content\/uploads\/archive\/2019\/04\/Sickle-cell-Trait.jpg\")
rn<\/p>\n![\"\"](\"https:\/\/mtctheme.medicaltourismco.com\/wp-content\/uploads\/2024\/06\/GIOSTAR-Los-AlgodonesMX.jpg\")
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